1,845+ Reviews
WHAT EVERY WELLNESS ROUTINE IS MISSING
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RELIEVES PAIN & PHYSICAL DISCOMFORT
Tired of dealing with everyday pain? Methylene Blue+ helps ease inflammation & discomfort by supporting your body at the cellular level so you can feel better, move easier, and enjoy more of what you love.
CLEARS BRAIN FOG & SHARPENS FOCUS
Feel like your mind’s in a fog? Methylene Blue+ helps fire up your brain’s energy engines so you can think clearly, stay focused, and power through your day with confidence and clarity.
SUPPORTS IMMUNITY, LONGEVITY & RESILIENCE
Methylene Blue+ strengthens your immune system, protects your cells, and supports long-term health so your body stays resilient and better prepared to fight illness, including cancer.
BOOSTS ENERGY & PERFORMANCE
Whether you're juggling a busy day or pushing through a workout, Methylene Blue+ fuels your body and mind so you feel energized, focused, and ready for whatever comes next.
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We believe in results you can feel. That’s why every order is backed by a 60-day money-back guarantee. If you’re not noticing a real difference, just send us an email. No questions asked, no hassle, full refund.
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Rated 4.8/5 by 14k+ Happy Customers
Naturalis Methylene Blue+ Drops
Increases Oxygen Levels
Boosts Your Energy & Metabolism
Relieves Chronic Pain
Improves Brain Function
Backed by 234+ Studies
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60 DAY MONEY-BACK GUARANTEE
I’ve been using Naturalis Methylene Blue as part of my daily routine to fight oxidative stress. It’s one of the best tools for mitochondrial function and lowering inflammation.
John C.
How does Methylene Blue+ work?
Methylene blue works like this: inside your body, there are tiny things called mitochondria.
They’re like little power plants in your cells, and their job is to make energy.
This energy is called ATP , and it’s what keeps your body running, like gas for a car.
Sometimes, mitochondria get tired or don’t work properly, and they can’t make enough energy.
That’s where Methylene Blue comes in.
It’s like a helper that supports the mitochondria and helps them make energy more efficiently.
It does this by helping the mitochondria use oxygen better and move electrons (tiny energy pieces) where they need to go.
When your mitochondria are working better, your body gets more energy, and you feel better, stronger, and healthier.
Is Methylene Blue+ safe to use?
Methylene Blue has been tested in human trials without any reported adverse effects. It is considered safe at therapeutic doses, which are less than 2 mg/kg—approximately 140 mg for a 70 kg individual.
Recent trials involving over 2800 participants have indicated that Methylene Blue can significantly enhance cognitive function and decrease brain atrophy. No adverse effects were reported in these studies.
*This is not medical advice, always seek the advice of a licensed physician before taking methylene blue*
Dosage + Usage Instructions
A common and research-backed method of using Methylene Blue is as follows:
Day 1: 5 drops (1.25 mg)
Day 2: 10 drops (2.5 mg)
Day 3: 20 drops (5 mg)
Day 4+: Continue with 20-40 drops daily (5-10 mg)
Weekly: Take 2 days off (e.g., weekends or midweek)
Please remember that the optimal dose may vary from person to person. If you experience any adverse effects, do not increase the dosage. Start with a low dose, monitor your body's response, and adjust to find the dose that works best for you.
60 Day Guarantee
Try Methylene Blue risk-free for 60 days. If you're not completely satisfied how good you'll feel after taking it, simply email us for a full refund. No questions asked.
Shipping & Returns
Shipping
Orders are typically processed within 1-3 business days, and you will receive a tracking number once your package is on its way. You can expect your order to arrive within 6-10 business days once shipped!
Returns
We want you to love your purchase! If you're not completely satisfied, you can return your item within 60 days of delivery for a full refund. Click here to learn how we can help.
Lab Verified Results
We don’t just claim purity, we back it up. Our formula is independently verified to be 99.9% pure, USP grade, and free from heavy metals. Click the image below to view our third-party lab results.
Lab Results
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3RD-PARTY TESTED
Trusted By 14k+ Customers
What is Methylene Blue+?
Methylene Blue, is a versatile salt renowned for its health-promoting benefits. Initially used in 1891 to treat malaria, this compound has stood the test of time, showcasing its reliability and efficacy.
Experienced More Energy & Sustained Focus
No Longer
Had Brain Fog
Experienced Less Chronic Pain & Inflammation
*Based off customer feedback
Methylene Blue+ Benefits
Experience real, science backed support for your mind, body, and long term wellness, starting with just a single drop.
Proven by Science
Methylene blue has shown measurable benefits for memory, mood, and brain function in multiple human clinical trials.
Real People
Real Benefits
Real People
“ENERGY, MOOD, AND FOCUS ON POINT”
Anthony T.
I’ve tried a lot of supplements that claim to help with focus, but this is the first one that gave me a noticeable difference without feeling overstimulated. About an hour after taking it, I felt more present, alert, and mentally organized. It’s like my brain just worked better.
12 hrs
Like
Reply
Message
215
“LIFTED MY MOOD AND GOT ME MOVING”
Angie M.
I wasn’t expecting much, but Methylene Blue gave me a calm sense of energy that actually made it easier to get things done. I felt lighter mentally, more optimistic, and less sluggish.
2 Days
Like
Reply
Message
51
Real Benefits
Increases Energy
|
Boosts Brain Function
|
Sharpens Focus
|
Lifts Mood
|
Increases Energy
|
Boosts Brain Function
|
Sharpens Focus
|
Lifts Mood
|
Increases Energy
|
Boosts Brain Function
|
Sharpens Focus
|
Lifts Mood
|
Increases Energy
|
Boosts Brain Function
|
Sharpens Focus
|
Lifts Mood
|
Memory.
Gain amplified capacity to recall and store information. Improves both short and long term memory.
Mood.
Feel a sustainable lift in mood, thanks to Methylene Blue’s serotonin and dopamine increasing properties.
Energy.
By improving mitochondiral energy production and ATP, Methylene Blue delivers noticeable increase in energy.
Antioxidant.
Methylene Blue functions as a robust antioxidant, battling free radicals & safeguarding your cells from oxidative damage.
Naturalis
USP Pharmaceutical Grade
Third-Party Lab Testing
Heavy Metal Free
No Toxic Solvents
Formaldehyde Free
Others
60 Day Money Back Guarantee
You got questions. We got answers.
Frequently Asked Questions
Does Methylene Blue contain heavy metals?
Only poor quality and purity Methylene Blue can contain heavy metals. We ensure the safety of our product by conducting continuous third-party laboratory tests on our batches.
Can I take this with antidepressants or other medications?
No, this product should not be taken with antidepressants or any medication that affects serotonin levels. If you're currently on medication, please consult your doctor before use to avoid any potential interactions.
How long does it take to start working?
Most users feel noticeable effects within 30–60 minutes of taking it. Memory, focus, and mental clarity continue to improve with consistent use over time.
Are there scientific studies supporting the benefits of methylene blue?
Yes! Over 234+ scientific studies have explored its effects. Research shows it enhances memory retrieval, supports mitochondrial function, and may help with cognitive decline. Studies have also found benefits for Alzheimer’s patients and brain energy metabolism.
"I feel a little run down after my first dose..."
Methylene Blue is very antipathogenic! When you introduce it into your system at first you can have what is known as Herxheimer effect. This is due to MB killing off any pathogens in the body. If you suspect you’re having a Herxheimer reaction, stop taking MB for a few days, drink plenty of fluids, and try a smaller dose!
4.8 (1847 reviews)
Laura B.
This is the first supplement that made me feel like my old self. I deal with chronic fatigue and autoimmune flares, but since using this, I’ve felt more clear-headed and less exhausted. Even my husband commented I seem happier.
Kevin R.
This stuff gives me a subtle but steady mental boost all day. Didn’t expect much but this really surprised me.
Sammy C.
I only need three drops a day of this to have incredible energy and a much better mood. It is pure gold. I have also noticed much more rich and vibrant dreams at night. Just start slow because it is powerful. My husband can take 15 drops a day. But I have found that just three drops is my magic number. And there is a great book out about it that I suggest reading. It is called The Ultimate Guide to Methylene Blue by Mark Sloan.
Johnny R.
I am really blown away and
amazed with this product. I
have so much energy and my
mind seems to be working so
well. Do not use if you are
using SSRI’s please check all
counter indications if you are
taking any pharmaceuticals.
Ben G.
It gives me this clear-headed focus I haven’t had in years. Glad I found this brand, no weird side effects.
Danny K.
My memory feels like it’s
actually improving, which is
wild.
Jasmine S.
For anyone who remembers
that day in elementary school
when the world seemed less
bright and it never went back,
this is what you're looking for.
Dawn P.
If you are looking for a high quality methylene blue brand that does not contain any metals, then this bottle is for you! I tossed my previous bottle in the trash, which was a different brand, because it contained arsenic & metals.
Kara L.
I didn’t expect much but was blown away. My memory improved, I can focus at work, and my morning aches are almost gone. I even started recommending it to friends with similar issues.
Landon D.
This stuff gives me a subtle but steady mental boost all day. Felt the difference within the first couple of days.
James H.
As a 46-year-old always on the hunt for ways to keep my mind sharp and my energy steady, this little bottle of Methylene Blue has been a surprising gem. It’s pharmaceutical-grade and third-party tested, so I feel confidentabout the quality. I noticed a subtle but steady boost in mental clarity and focus within days. It’s like my brain got a tune up without the jitters of caffeine.
Sarah B.
This is helped with my energy and my thinking ability. It's not that expensive but it works so really really good (I know bad grammar) it just made me feel much better, it actually works.
Amber G.
My energy levels are finally
consistent throughout the day. No more struggling to stay awake in the afternoon!
Robert S.
I used to need multiple
coffees just to function, but
now I wake up feeling
refreshed and ready to go.
Rebecca W.
I’ve noticed my pain and
inflammation going down a
lot. Felt the difference within
the first couple of days.
Tammy D.
I've used this Methylene Blue (MB) for four days in a row now. Great results so far: more energy and improved mental clarity. What I especially like about the effect off MB is that the energy/clarity boost is subtle. There's no jittery feeling, burst of energy, or crash like you get with caffeine. It seems to raise my baseline level of physical and mental functionality in a noticeable but not overwhelming way.
Shannon S.
I take Methlyene Blue (MB) for my eye health after a member on a forum for glaucoma said on a checkup his ophtho was surprised to see improvement in his optic nerve, which is unheard of. Makes sense though since MB functions as an electron donor to help mitochondria and nerve malfunction is due to mitochondrial dysfunction. I take 20 drops a day in 2 divided doses. As soon as I wake up and after lunch. It gives me energy so I don't want to take it in the evening. This is a high quality product made in the USA and I will be ordering again.
Robert D.
This has completely changed
my focus at work. I feel
sharper, more alert, and no
longer get that mid-day
crash. Definitely buying again.
Brooke S.
I feel calmer and less anxious overall, it’s like my mood has lifted. Started slow and the results just kept building.
Natasha L.
I had no idea how much I needed this. I've been taking this Methylene Blue supplement for about a week now and it's a game-changer for anyone looking to enhance brain function and cognitive health. I'm 45 years old and in pretty good health but in the last 2 years have become so tired and I feel like I'm in a fog mentally. Since taking Methylene Blue I've experienced a noticeable improvement in mental clarity and focus. It's like the fog is lifting and I have more energy in the day.
Susan J.
My productivity has doubled
since I started taking this. I
can actually finish tasks now.
Natalie F.
I’ve tried so many things for brain fog, but nothing worked until this. I can focus for hours without distractions now.
Victoria H.
I have ADHD, and this helps me stay on task so much better than anything else I’ve tried.
Thomas B.
My mental stamina has improved so much. I can focus on tasks for hours without feeling drained.
4.9 (2145 reviews)
Nancy H.
This is the first supplement that made me feel like my old self. I deal with chronic fatigue and autoimmune flares, but since using this, I’ve felt more clear-headed and less exhausted. Even my husband commented I seem happier.
Kara L.
I didn’t expect much but was blown away. My memory improved, I can focus at work, and my morning aches are almost gone. I even started recommending it to friends with similar issues.
Brooke S.
I feel calmer and less anxious overall, it’s like my mood has lifted. Started slow and the results just kept building.
Danny K.
My memory feels like it’s actually improving, which is wild.
Tammy D.
I've used this Methylene Blue (MB) for four days in a row now. Great results so far: more energy and improved mental clarity. What I especially like about the effect off MB is that the energy/clarity boost is subtle. There's no jittery feeling, burst of energy, or crash like you get with caffeine. It seems to raise my baseline level of physical and mental functionality in a noticeable but not overwhelming way.
Sammy C.
I only need three drops a day of this to have incredible energy and a much better mood. It is pure gold. I have also noticed much more rich and vibrant dreams at night. Just start slow because it is powerful. My husband can take 15 drops a day. But I have found that just three drops is my magic number. And there is a great book out about it that I suggest reading. It is called The Ultimate Guide to Methylene Blue by Mark Sloan.
James H.
As a 46-year-old always on the hunt for ways to keep my mind sharp and my energy steady, this little bottle of Methylene Blue has been a surprising gem. It’s pharmaceutical-grade and third-party tested, so I feel confidentabout the quality. I noticed a subtle but steady boost in mental clarity and focus within days. It’s like my brain got a tune up without the jitters of caffeine.
Dawn P.
If you are looking for a high quality methylene blue brand that does not contain any metals, then this bottle is for you! I tossed my previous bottle in the trash, which was a different brand, because it contained arsenic & metals.
Ben G.
It gives me this clear-headed focus I haven’t had in years. Glad I found this brand, no weird side effects.
Rebecca W.
I’ve noticed my pain and inflammation going down a lot. Felt the difference within the first couple of days.
Kevin R.
This stuff gives me a subtle but steady mental boost all day. Didn’t expect much but this really surprised me.
Landon D.
This stuff gives me a subtle but steady mental boost all day. Felt the difference within the first couple of days.
Natasha L.
I had no idea how much I needed this. I've been taking this Methylene Blue supplement for about a week now and it's a game-changer for anyone looking to enhance brain function and cognitive health. I'm 45 years old and in pretty good health but in the last 2 years have become so tired and I feel like I'm in a fog mentally. Since taking Methylene Blue I've experienced a noticeable improvement in mental clarity and focus. It's like the fog is lifting and I have more energy in the day.
Jasmine S.
For anyone who remembers that day in elementary school when the world seemed less bright and it never went back, this is what you're looking for.
Shannon S.
I take Methlyene Blue (MB) for my eye health after a member on a forum for glaucoma said on a checkup his ophtho was surprised to see improvement in his optic nerve, which is unheard of. Makes sense though since MB functions as an electron donor to help mitochondria and nerve malfunction is due to mitochondrial dysfunction. I take 20 drops a day in 2 divided doses. As soon as I wake up and after lunch. It gives me energy so I don't want to take it in the evening. This is a high quality product made in the USA and I will be ordering again.
Johnny R.
I am really blown away and amazed with this product. I have so much energy and my mind seems to be working so well. Do not use if you are using SSRI’s please check all counter indications if you are taking any pharmaceuticals.
Susan J.
My productivity has doubled since I started taking this. I can actually finish tasks now.
